2011-2012 Basic and Clinical Science Course, Section 4: by Robert H. Rosa Jr., MD

By Robert H. Rosa Jr., MD

This quantity is split into elements: half I, Ophthalmic Pathology; and half II, Intraocular Tumors: medical features. half I makes use of a hierarchy that strikes from basic to precise to aid derive a differential analysis for a particular tissue. half II is a compilation of chosen scientific features of value to the overall ophthalmologist. Following half II are the yankee Joint Committee on melanoma 2010 staging types for ocular and adnexal tumors. This revised textual content comprises a variety of new pathologic and medical pictures. significant revision 2011-2012.

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Extra resources for 2011-2012 Basic and Clinical Science Course, Section 4: Ophthalmic Pathology and Intraocular Tumors (Basic & Clinical Science Course)

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Targets must be different enough to form distinct bands when visualized by gel electrophoresis. M icrofluidic chip allows automation and clinical use. Known type and location of expected aberrations Quality snap-frozen tissue (optimal) and archival paraffin embedded tissue 1. Variable success rate of DNA extraction 2. Contamination with other nucleic acid material CHAPTER 4: Special Procedure s . 39 Table 4·2 (continued) Technique Method Advantages Disadvantages Reverse tra nscriptasepolym erase cha in react ion (RT-PCR ) Amplifi es DNA from RNA.

Li mbal papillae may occur in vernal keratoconj un ctivitis (Horner~ Trantas dots). The histologiC appea rance of papillar y conjunctivi tis is identi cal, regardless of the cause: closely packed, flat~ topped projections, with numerous eos i no ~ phils, lymphocytes, plas ma cells, and mast cells in the stroma surrounding a central vas~ cular channel. CHAPTER 5: Conjunctiva. 51 B Figure 5-3 Schematic representation of papil lary and follicular conjunctivit is. A, In papillary conjunctivitis, the conjunctival epithe lium (checkered blue) covers fibrovascular core s w ith blood vessels (red), and the stroma contains eosinophils (pink circles) and lymphocytes and plasma cells (blue circles).

Episcleral osseous choristoma and osseocartilaginous choristoma complex choristoma Dermoids are finn, dome-shaped, white-yellow papules typically at or straddling the limbus, most commonly in the inferotemporal quadrant (Fig 5-2A, B). They may also in volve the central cornea. Size varies from a few millimeters to more than 1 cm. Dermoids may occur in isolation or. particularly when bilateral, as a manifestation of a congenital complex such as Goldenhar syndro me (oculoauriculovertebral dysgenesis, characterized by epibulbar dermoid, upper eyelid coloboma, preauricular skin tags, and vertebral anomalies) or linear nevus sebaceous syndro me (an oculoneurocutaneous disorder), A dermoid often contai ns dermal adnexal structures.

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