By Abel Lajtha and Donald H. Ford (Eds.)
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1966) The ultrastructural basis of capillary permeability. In: The /irflamt~ra/oryProcess, B. W . :, 1, Ch. 3, 121-159. MAXWELL, D. S. AND PEASE,D. C. (1956) The electron microscopy of the choroid plexus. J . Biophys. Biochem. , 2, 467-474. PAPPAS,G. D. AND TENNYSON, V. M. (1962) An electron microscopic study of the passage of colloidal particles from the blood vessels of the ciliary process and choroid plexus of the rabbit. J . , 15, 227-240. PAPPAS,G . D. AND PURPURA, D. P. (1966) Distribution of colloidal particles in extracellular space and synaptic cleft substance of mammalian cerebral cortex.
Cleutsch. Ges. Chirurgie, 42, 107-1 13. KARNOVSKY, M. (1965) Vesicular transport of exogenous peroxidase across capillary endothelium into the T-system of muscle. J . Cell. , 27, 49A. KING,L. (1938) The hematoencephalic barrier. Arch. Neurol. , 41, 51-72. , MIQUEL, J. AND OTENASEK, R. (1962) The application of fluorescein labeled serum proteins (FLSP) to the study of vascular permeability in the brain. , 2, 144-160. KUFFLER, S . W. AND NIcHoLLS, J. G . (1966) The physiology of neuroglial cells.
The size, from molecular weight measurements, is about 70 Angstroms of these compounds, which well fits within the usual structural arrangement as we picture the membranes. DOBEING: I wonder if you could make any statement about the turnover of these particles that we are discussing, especially since they are often buried beneath several layers, of, for example, proteolipids which, in themselves, do not turn over very rapidly? Is it possible to account for all the turnover as being the turnover of only the exterior part of the sheaths?