Cardiac Biomarkers: Case Studies and Clinical Correlations by Alan S. Maisel, Allan S. Jaffe

By Alan S. Maisel, Allan S. Jaffe

This e-book covers ACS and center Failure, the chapters characterize the most up-tp-date, brand new and a professional content material at the subject on hand. it really is written via the worlds most precious leaders in biomarkers, with a majority emphasis on what clinicians have to know.
The Editors and their individuals have supplied algorithms, annotated case discussions and caveats. They conceal biomarkers to foretell threat of middle ailment, biomarkers of cardiorenal sickness , and finish with a piece on new and rising biomarkers. it's surely useful and sensible to these within the box, together with not only humans operating within the box, yet nurses, medical professionals, and so on who perform medication within the health facility, the emergency division and the hospital.​

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The main reason for this is that high sensitivity troponin assays report to three decimal places if the current units of micrograms/L are used. This creates a risk when results are viewed as human beings cope much better with numbers to the left of the decimal point. In addition there is a significant risk with electronic data transfer. There is an unfortunate tendency in some software packages (from electronic messaging to electronic patient record programs) to round decimal points. Potentially this might give a result of zero for an elevated troponin value.

16. Sandoval Y, Smith SW, Schulz KM, Murakami MM, Love SA, Nicholson J, Apple FS. Diagnosis of type 1 and type 2 myocardial infarction using a high-sensitivity cardiac troponin I assay with sex-specific 99th percentiles based on the third universal definition of myocardial infarction classification system. Clin Chem. 2015;61:657–63. 17. Korley FK, Jaffe AS. Preparing the United States for high-sensitivity cardiac troponin assays. J Am Coll Cardiol. 2013;61:153–8. 18. Newby LK, Jesse RL, Babb JD, Christenson RH, De Fer TM, Diamond GA, Fesmire FM, Geraci SA, Gersh BJ, Larsen GC, Kaul S, McKay CR, Philippides GJ, Weintraub WS.

Rapid exclusion of acute myocardial infarction in patients with undetectable troponin using a high-sensitivity assay. J Am Coll Cardiol. 2011;58:1332–9. 8. Bandstein N, Ljung R, Johansson M, Holzmann MJ. Undetectable high-sensitivity cardiac troponin T level in the emergency department and risk of myocardial infarction. J Am Coll Cardiol. 2014;63:2569–78. 9. Body R, Burrows G, Carley S, Cullen L, Than M, Jaffe AS, Lewis PS. High-sensitivity cardiac troponin T concentrations below the limit of detection to exclude acute myocardial infarction: a prospective evaluation.

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