By Robin G. Shanks (eds.)
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MASERI, A. & MANCINI, P. (1971). The evaluation of regional myocardial perfusion in man by a scintillation camera computer system. In Myocardial blood flow in man. Methods and significance in coronary disease, ed. , pp. 219-230. Torino: Minerva Medica. , MICHELASSI, C. & D'ANGELO, T. (1974). Contribution of recirculation and fat diffusion to myocardial washout curves obtained by external counting in man. , 35, 826-834. Jr. A. (1959). The effects of theophylline ethylene diamine (aminophylline) on the coronary hemodynamics of normal and diseased hearts.
1977). Effects of Propranolol on the haemodynamic coronary sinus blood flow and myocardial metabolic response to atrial pacing. Am. J. • 40, 83-89. L. H. (1971). Myocardial perfusion imaging with radioactive-labelled particles injected directly into the coronary circulation of patients with coronary artery disease. Circulation. 44, 851-865. A. R. (1976). Coronary perfusion and myocardial metabolism during open heart surgery in man. J. Thorae. Cardiovase. , 72, 133-141. B. (1977). Physiology and theory of tracer washout techniques for the estimation of myocardial blood flow: flow estimation from tracer washout.
The angle of the jet is directed into the stream of coronary sinus blood to facilitate mixing (Fronek & Ganz, 1960). Infusion of the cold saline results in a rapid rise in resistance of the internal (indicator) thermistor and a slower rise in resistance of the external (dilution) thermistor as the saline/blood mixture equilibrates. The external thermistor is mounted on the same side of the catheter as the jet orifice to keep the thermistor away from the coronary sinus wall. A high infusion rate of saline (35-55 ml/min) is requiring to ensure adequate mixing (Bing, Rickart & Hellberg, 1972).