Cardiovascular Therapeutics: A Companion to Braunwald's by Elliott M. Antman MD

By Elliott M. Antman MD

Manage cardiovascular difficulties extra effectively with the main complete source to be had! A depended on significant other to Braunwald's center Disease, Cardiovascular Therapeutics, 4th Edition addresses pharmacological, interventional, and surgical administration techniques for every kind of heart problems. This sensible and clinically targeted cardiology reference deals a balanced, whole method of all the ordinary and strange components of heart problems and particular treatments in a single concise quantity, equipping you to make the easiest offerings for each patient.

  • Understand present techniques to treating and coping with cardiovascular patients
  • for long term well-being, for complicated difficulties, and for strange cardiac events.

  • Benefit from the enormous event of Elliott M. Antman, MD, Marc S. Sabatine, MD, and a number of different revered experts, who offer sensible, evidence-based rationales for all of brand new medical therapies.
  • Expand your wisdom past pharmacologic interventions with whole insurance of the best interventional and equipment cures getting used today.
  • Easily reference Braunwald's center sickness, ninth Edition for extra info on themes of interest.

  • Make the easiest use of the most recent genetic and molecular therapies
  • in addition to advanced remedies for center failure.

  • Cut correct to the solutions you would like with an superior concentrate on clinically appropriate info and a lowered emphasis on pathophysiology.
  • Stay present with ACC/AHA/ESC guidelines and the simplest how one can enforce them in scientific practice.
  • Get an improved visible perspective with an all-new, full-color layout throughout.
  • Access the total contents online and download images at

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Additional info for Cardiovascular Therapeutics: A Companion to Braunwald's Heart Disease

Example text

The curve consists of three parts: the survival pattern in the first year after treatment in the Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries (GUSTO) study, data for an additional 14 years on survivors of myocardial infarction in the Duke Cardiovascular Disease Database, and a Gompertz parametric survival function adjusted to agree with the empirical survival data at the 10and 15-year follow-up points. (From Mark DB, Hlatky MA, Califf RM, et al.

Were the primary studies of high methodologic quality? Were assessments of studies reproducible? How Can I Apply the Results to Patient Care? Were all patients-important outcomes considered? Are any postulated subgroup effects credible? What is the overall quality of the evidence? Are the benefits worth the costs and potential risks? From Guyatt G, Jaeschke R, Prasad K, Cook DJ. Summarizing the evidence. In Guyatt G, Rennie D, Meade MO, Cook DJ, editors: Users’ guides to the medical literature: a manual for evidence-based clinical practice, 2nd ed, New York, 2008, McGraw-Hill, p 527.

These analyses may be represented as a Probability of Survival numerous assumptions about treatment outcomes, especially when appropriate data do not exist. Although the impact of these choices can be evaluated in sensitivity analyses (detailed below), adequately evaluating the validity of these models can be complex, and it limits their transparency for nonexpert readers. 450,000 400,000 350,000 300,000 250,000 200,000 150,000 5% 100,000 9% 50,000 0 0% 2% 4% 6% 8% 10% 12% 14% 16% 18% 20% 22% 24% 26% 28% 30% Increase in time in target INR range FIGURE 1-19 One-way sensitivity analysis of the impact of improvements in anticoagulation control using genotypic warfarin dosing on the cost effectiveness of this treatment strategy compared with algorithm-based warfarin dosing.

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