By Kyoichi Mizuno, Masamichi Takano
This ebook provides a radical evaluation of coronary angioscopy, starting from directions on its use to the most recent advances. beginning with the constitution and basic rules of angioscopy, it exhibits readers find out how to follow the picture to finished care of coronary-artery sufferers. considerable colour photographs and illustrations will permit readers to enquire and classify plaques and thrombi and to guage coronary stent- and drug-based cures. The authors are prime researchers on angioscopy. This ebook bargains the best advisor not just for brand new clinicians but additionally for cardiologists who've already followed this method for clinical exam and therapy. Angioscopy is a different clinical procedure for visualizing the inner of blood vessels and is helping physicians not just to diagnose the pathology but additionally to degree the effectiveness of Percutaneous coronary intervention (PCI) or antiarteriosclerotic medicines. in addition, the lately built molecular angioscopy process permits us to monitor Low-density lipoprotein (LDL) oxide, collagen, and macrophages, and is swiftly transforming into in importance.
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Uchida Y, Uchida Y, Sakurai T, Kanai M, Shirai S, Oshima T, Koga A, Matsuyama A. Possible role of damaged neoendothelial cells in the genesis of coronary stent thrombus in chronic phase. Int Heart J. 2011;52:12–6. 8. Uchida Y, Uchida Y, Sakurai T, Kanai M, Shirai S, Oshima T, Koga A, Matsuyama A, Tabata T. -An angioscopic study. Circ J. 2010;75:2379–85. 9. Uchida Y, Uchida Y, Shirai S, Oshima T, Shimizu K, Tomaru T, Sakurai T, Kanai M. Angioscopic detection of pulmonary thromboemboli: with special reference to comparison with angiography, intravascular ultrasonography and computed tomography angiography.
001). 001). 001). 2). 1 Clinical and Imaging Features of IFC-ACS In our group of ACS patients presenting with NSTEMI or unstable angina, 30 % were not associated with fibrous cap rupture. The prevalence of current smokers and the proportion of females were higher in these patients compared to the RFC group [9, 10]. 22 Y. Ozaki et al. Fig. 2 Intact fibrous cap (IFC-ACS) plaque. OCT (a), coronary angioscopy (b), IVUS (c), angiography (d), volume-rendered (e) and curved MPR (f) images were derived from a culprit lesion with intact fibrous caps in a 63-year-old male presenting with an ACS.
The fluffy surface was stained blue with EB, indicating the presence of fibrin and/or damaged endothelial cells (Fig. 7). Similar changes were reproduced by mechanical damages to the artery followed by blood perfusion to produce thrombus in dogs. Fluffy surface was exposed after removal of globular thrombus. Histologically, the fluffy surface was composed of fibrin threads arising from the damaged endothelial cells and adhered by platelets. Therefore, we consider that coronary segment with frosty glass-like surface is the site of surface disruption and resultant thrombosis and frosty glass-like changes are due to residual fibrin and platelets after autolysis of the thrombus [3, 5, 8].