DNA Computing and Molecular Programming: 21st International by Andrew Phillips, Peng Yin

By Andrew Phillips, Peng Yin

This booklet constitutes the refereed court cases of the twenty first foreign convention on DNA Computing and Molecular Programming, DNA 21, held in Boston and Cambridge, MA, united states, in August 2015.

The thirteen complete papers awarded have been rigorously chosen from sixty three submissions. The papers deal with all present concerns relating to biomolecular computing, similar to: algorithms and types for computation on biomolecular structures; computational strategies in vitro and in vivo; molecular switches, gates, units, and circuits; molecular folding and self-assembly of nanostructures; research and theoretical types of laboratory ideas; molecular automobiles and molecular robotics; reports of fault-tolerance and mistake correction; software program instruments for research, simulation, and layout; man made biology and in vitro evolution; purposes in engineering, physics, chemistry, biology, and medicine.

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Extra info for DNA Computing and Molecular Programming: 21st International Conference, DNA 21, Boston and Cambridge, MA, USA, August 17-21, 2015. Proceedings

Example text

Furthermore, both classes have well-studied theoretical models, including a variety of self-assembly models based on Wang tiling [11,16] and models of abstract chemical reaction networks for chemical dynamics [6,8,27,28]. Despite the well-established results in these fields, little theoretical work has considered interactions between structural and dynamic DNA nanotechnology, suggesting that current theoretical models do not capture the full computational power of biomolecular systems. In biological systems, structure influences dynamics, and dynamics influences structure: the two are inextricably linked together.

It is possible that better circuits will be found by considering CRNs with more reactions, species, and longer computation paths. 1 Before optimisation After short optimisation #3 9 #4 9 4, 4 D #10 iv 5 4 D ,4 # iv 4 1 4 D ,4 #3 iv 2 4, 4 # 12 #2 4 4 D ,4 iv 4 D ,4 iv D 4,4 iv 4 D ,3 #2 iv D 4,3 # iv 4 4 D ,3 # iv 25 4 D ,3 #2 iv 3 4, 3 D #1 iv 9 D 4,3 # iv 3 3 D ,3 #1 iv D 3,3 # iv 2 4, 3 D #2 iv 9 D iv 3 D ,3 #1 iv 2 3, D 3 # iv 16 3, 3 D #17 iv 3 D ,3 # iv 0 3, 3 D #1 iv 4 0 After long optimisation Fig.

Phys. Chem. 81, 2340–2361 (1977) 28. : Markov Processes: Characterization and Convergence, vol. 282. edu Abstract. Tile-based self-assembly and chemical reaction networks provide two well-studied models of scalable DNA-based computation. Although tile self-assembly provides a powerful framework for describing Turing-universal self-assembling systems, assembly logic in tile selfassembly is localized, so that only the nearby environment can affect the process of self-assembly. We introduce a new model of tile-based self-assembly in which a well-mixed chemical reaction network interacts with self-assembling tiles to exert non-local control on the self-assembly process.

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