The Role of Oxygen Radicals in Cardiovascular Diseases: A by Lars Ernster (auth.), A. L’Abbate, F. Ursini (eds.)

By Lars Ernster (auth.), A. L’Abbate, F. Ursini (eds.)

Growing experimental facts is beeing produced in help of the thesis that lipid pe,oxidation is a crucial mediator of either vascular and myocardial tissue derangement. even supposing the position of the free-radical method in human cardiovascular pathology continues to be speculative, however the aptitude implications of this type of process in either pharmacological treatment and prevention of significant cardiovascular ailments, comparable to myocardial infarction, cardiomyopathy and arrhythmias, justify the expanding curiosity of scientific cardiologists during this learn zone. in addition, present-day medical cardiology allows to breed in guy such experimental types as ischemia and reperfusion, e.g. in the course of percutaneous transluminal angioplasty, or even to achieve histological and histochemical entry to byoptic myocardial tissue. Upon above premises the assumption of a multidisciplinary dialogue assembly used to be conceived, aimed to confront scientific expectancies with received uncomplicated info, and to debate the validity of experimental versions within the gentle of pathological and medical findings in guy. To this objective, a distinct crew of specialists within the box of free-radicals, from world wide, was once requested to make the subject obtainable to scientific cardiologists, with the first target of projecting effects and ideas in the direction of strength scientific learn; this is often, in truth, the thing of the eu Concerted motion "Breakdown in Human model - Cardiovascular Diseases", within the body of which the assembly was once held.

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The Role of Oxygen Radicals in Cardiovascular Diseases: A Conference in the European Concerted Action on Breakdown in Human Adaptation — Cardiovascular Diseases, held in Asolo, Italy, 2–5 December 1986

Becoming experimental facts is beeing produced in help of the thesis that lipid pe,oxidation is a vital mediator of either vascular and myocardial tissue derangement. even though the function of the free-radical process in human cardiovascular pathology is still speculative, however the capability implications of this type of procedure in either pharmacological treatment and prevention of significant cardiovascular ailments, comparable to myocardial infarction, cardiomyopathy and arrhythmias, justify the expanding curiosity of scientific cardiologists during this study zone.

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Extra resources for The Role of Oxygen Radicals in Cardiovascular Diseases: A Conference in the European Concerted Action on Breakdown in Human Adaptation — Cardiovascular Diseases, held in Asolo, Italy, 2–5 December 1986

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M. L. Dormandy FEBS Lett. 162, (1983) 239. 28. A. Iversen, P. J. M. L. Dormandy : Life Chern. Rep. 3, (1985) 45. 29. G. F. H. R. L. Dormandy : Free Radical Res. Comms. 1987, in press. 30. A. Iversen, P. L. Dormandy : Ann. Clin. Biochem. 22, (1985) 137. 31. R. S. R. C. O. Lundberg: Ind. Eng. Chern. 49 (1957) 1713. 32. S. Bergstrom: Ark. Kern. Mineral. Geol. 21A (1945) 1. 33. 1. Ivanov: J. Free Rad. BioI. Med. 1, 34. S. T. Smith 35. M. R. Clemens, H Einsele, H. D. Waller Clin. Chim. Acta. 145, (1985) 283.

36. E. Hughes and S. B. Tove : J. BioI. Chern. 255, 1802. 37. W. Parodi: J. Dairy Sci. 60, (1977) 1550. 38. T. J. T. ), vol. 9, pp. 13-90. Pergamon, Oxford, 1966. 39. S. Markley : Fatty Acids, their Characteristics and Properties: Vol. 1. Wyley, New York, 1948. 40. R. H. R. Clemens, P. Patsalos, P. A. L. Dormandy : Lancet 2, (1985) 291. 41. R. H. R. Clemens, P. Patsalos, P. A. L. Dormandy : Lancet 2, (1985) 291. 42. R. Clemens and H. Einsele : in Free Radicals (C. ), pp. 127-131. Richelieu, London 1986.

S. Lieber : Dig. Dis. Sci. 28, (1983) 585. 25. G. H. Wilkins, J. Lunec, G. L. Dormandy : Ann. Clin. Biochem. 18, (1981) 158. 26. J. P. G. L. Dormandy J. Rheumatol. 8, (1981) 233. Lab. Invest. 15, (1966) Biochem. Arch. Biochem. Biochim. Gastro- 49 27. P. G. A. M. L. Dormandy FEBS Lett. 162, (1983) 239. 28. A. Iversen, P. J. M. L. Dormandy : Life Chern. Rep. 3, (1985) 45. 29. G. F. H. R. L. Dormandy : Free Radical Res. Comms. 1987, in press. 30. A. Iversen, P. L. Dormandy : Ann. Clin. Biochem. 22, (1985) 137.

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